Letrozole: What It Is and How It Helps

Letrozole is a medication usually prescribed to treat certain types of breast cancer. It belongs to a group called aromatase inhibitors, which work by lowering estrogen levels in the body. Because some breast cancers grow due to estrogen, reducing this hormone can slow or stop cancer growth.

You'll mostly find Letrozole used in postmenopausal women with hormone receptor-positive breast cancer. By cutting off estrogen, Letrozole helps keep cancer cells from multiplying. It’s often part of hormone therapy after surgery or radiation, helping prevent cancer from coming back.

Apart from cancer treatment, Letrozole has an off-label use that might surprise you: aiding fertility. When used carefully under a doctor’s guidance, it can help women who have trouble ovulating. This is especially true for those with polycystic ovary syndrome (PCOS), where ovulation doesn’t happen regularly.

Letrozole is taken as a pill, usually once a day. Dosage depends on the condition being treated, and it’s important to follow your doctor’s instructions closely to avoid side effects or complications. Common side effects include hot flashes, joint pain, and fatigue; these typically lessen over time.

Before starting Letrozole, discuss your full medical history with your doctor, especially if you have bone problems or liver issues, since Letrozole can affect bone density and liver function. Regular check-ups during use help catch any concerns early.

Is Letrozole safe? When taken as prescribed, it can be very effective and relatively safe, but it’s not for everyone. Pregnant or breastfeeding women should avoid it due to potential risks to the baby. Always keep open communication with your healthcare provider.

If you’re wondering about alternatives, your doctor might suggest other aromatase inhibitors or hormone therapies depending on your situation. The right choice depends on many factors like your cancer type, menopausal status, and overall health.

In short, Letrozole plays a critical role for many women battling breast cancer or facing fertility challenges. Understanding how it works and what to expect can empower you to make better health decisions in partnership with your medical team.