Generic Zyrtec-d (Cetirizine-pseudoephedrine 5mg)
1. Denomination
Zyrtec
2. Active Substance
Cetirizine
3. Indications for Use.
Seasonal and all-the-year-round allergic rhinitis, pollinosis, allergic conjunctivitis, chronic hives, skin itching, angioedema; it is used for a complex therapy of dermatitis, chronic eczema, bronchial asthma.
4. Action
The performance is developing during 1–2 hours after an intake. It soothes the symptoms of allergic rhinitis (sneezing, running nose, stuffed nose, itching, lacrimation). It effectively retards the development of skin reactions.
5. Posology and Administration
To adults and children of more than 12 years of age it is recommended to take 10 mg (1 tablet) of Cetirizine, preferably in the evening.
To children from 6 to 12 years of age and with body mass less than 30 kg it is recommended to take 5 mg (1/2 of a tablet) in the evening; to children with body mass more than 30 kg - 10 mg (1 tablet) in the evening. It is possible an intake of 5 mg (1/2 of a tablet) 2 times a day (in the morning and in the evening).
It is recommended to decrease a dose by two-fold to patients with kidney failure.
In disordersа of liver function a dose must be selected individually, especially carefully if there is also a kidney disorder.
People of advanced age with a normal function of kidneys do not need a dose correction.
In seasonal allergic rhinitis a therapy time duration for adults is usually from 3 to 6 weeks, whereas in short-time affect of an allergen 1 week therapy is enough. A therapy time duration for children more than 6 years of age is from 2 to 4 weeks, whereas in short-time affect of an allergen 1 week therapy is enough.
6. Counterindications
– severe kidney diseases;
– infancy and childhood under 6 years of age;
– pregnancy;
– lactation (breastfeeding);
– hypersensitivity to the drug components.
7. Should Be Taken with Precautions, if…
In chronic kidney failure of medium degree and a severe degree of manifestation (correction of a dosage regimen is needed), likewise in elderly patients.
With preсautions the drug is administered in chronic pyelonephritis of medium and heavy severity level (correction of a dosage regimen is needed), in elderly patients.
8. Interface with Other Medications
If there is a need to take the drug together with other medications it is necessary to consult your doctor in order to rule out a series of unwanted effects with a possible interface of the drugs.
9. Overdosing
A single-shot intake of the drug in a dose more than 50 mg may be accompanied with such signs of intoxication as drowsiness; in children an overdosage of the drug may be accompanied with anxiety and hyperirritability, signs of antiholinergic action may be manifested in the form of urine retention, dry mouth and constipation.
10. Side Effects
On the part of digestive system: dry mouth, indigestion.
On the part of central nervous system: headache, drowsiness, tiredness, dizziness, excitement, migraine.
Allergic reactions: skin rash, angioedema, hives, skin itching.
The drug usually is well tolerated. Side effects emerge seldom and have transitory character.
11. Pregnancy and Lactation
The drug is counterindicated for use in pregnancy. If the drug therapy in the period of lactation is needed, it is necessary to decide a question of cancellation of breast feeding.
12. Driving
In the period of the drug use it is necessary to avoid potentially hazardous activities, which require elevated concentration of attention and quickness of psychomotor reactions.
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