Generic Voltaren (Diclofenac 50mg)
DICLOFENAC
Tablets: 50 mg (as potassium) (Rx) Various, Cataflam (Novartis)
Tablets, delayed-release: 25, 50, and 75 mg Various, Voltaren (Novartis)
(as sodium) (Rx)
Tablets, extended-release: 100 mg (as sodium) (Rx) Voltaren-XR (Novartis)
Indications
Rheumatoid arthritis and osteoarthritis: Relief of signs and symptoms; treatment of acute flares and exacerbation; long-term management.
Concomitant therapy -Concomitant therapy with other second-line drugs (e.g., gold salts) demonstrates additional therapeutic benefit. Whether they can be used with partially effective doses of corticosteroids for a "steroid-sparing" effect and result in greater improvement is not established.
Use with salicylates is not recommended; greater benefit is not achieved, and the potential for adverse reactions is increased. The use of aspirin with non-steroidal anti-inflammatory agents (NSAIDs) may cause a decrease in blood levels of the non-aspirin drug.
Administration and Dosage
Osteoarthritis - 100 to 150 mg/day in divided doses (50 mg twice/day or 3 times/ day [diclofenac sodium or potassium] or 75 mg twice/day [diclofenac sodium]). Dosages > 200 mg/day have not been studied.
Rheumatoid arthritis - 150 to 200 mg/day in divided doses (50 mg 3 or 4 times/day [diclofenac sodium or potassium] or 75 mg twice/day [diclofenac sodium]). Dosages > 225 mg/day of the delayed-release diclofenac sodium formulation and dosages > 200 mg/day of immediate-release diclofenac potassium formulation are not recommended.
Ankylosing spondylitis - 100 to 125 mg/day as 25 mg 4 times/day, with an extra 25 mg dose at bedtime, if necessary. Dosages > 125 mg/day have not been studied.
Analgesia and primary dysmenorrhea (diclofenac potassium only) - Recommended starting dose is 50 mg 3 times/day. In some patients, an initial dose of 100 mg followed by 50 mg doses will provide better relief. After the first day, when the maximum recommended dose may be 200 mg, the total daily dose should generally not exceed 150 mg.
ARTHRITIS
PREVENTING OSTEOPOROSIS PROBLEM: EPIDEMIOLOGY OF THE DISEASE
Although many people consider osteoporosis to be a women's disease or a disease that afflicts the elderly, osteoporosis can occur at any age, and increasingly it seems to pose a problem for men too. When people hear that someone has osteoporosis, the image that comes to mind is a slumped-over individual with a characteristic "dowager's hump" in the upper back; however, this is a relatively rare, extreme version of the disease. Osteoporosis is progressive and occurs over many years, and without proper prevention in the form of diet, weight-bearing exercise, and overall fitness improvements, each of us risks developing this condition. As awareness increases, millions of Americans are demanding "bone density" tests to determine just how far gone their bones and joints really may be. Health care providers, responding to the estimated 14 billion dollars in direct and indirect costs that osteoporosis patients incur, are also motivated to focus on controlling risks.
Prevalence data about osteoporosis indicate the following:
- The hips, wrists, and spine are most vulnerable to the ravages of osteoporosis.
- In the United States, osteoporosis affects over 28 million Americans, 80 percent of whom are women.
- Each year 1.5 million fractures are caused by osteoporosis: 300,000 occur at the hip, 700,000 occur in the vertebrae, 250,000 occur in the wrists, and more than 300,000 occur at other sites.
- One out of every 2 women and 1 in 8 men over age 50 will have an osteoporosis fracture sometime in life.
- More than 2 million American men have osteoporosis and millions more are at risk. Each year, 80,000 men suffer a hip fracture and one third of these men die within a year.
*3/277/5*
HEALTHY BONES
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