Generic Voltaren Xr

DICLOFENAC
Tablets: 50 mg (as potassium) (Rx) Various, Cataflam (Novartis)
Tablets, delayed-release: 25, 50, and 75 mg Various, Voltaren (Novartis)
(as sodium) (Rx)
Tablets, extended-release: 100 mg (as sodium) (Rx) Voltaren-XR (Novartis)

Indications
Rheumatoid arthritis and osteoarthritis: Relief of signs and symptoms; treatment of acute flares and exacerbation; long-term management.
Concomitant therapy -Concomitant therapy with other second-line drugs (e.g., gold salts) demonstrates additional therapeutic benefit. Whether they can be used with partially effective doses of corticosteroids for a "steroid-sparing" effect and result in greater improvement is not established.
Use with salicylates is not recommended; greater benefit is not achieved, and the potential for adverse reactions is increased. The use of aspirin with non-steroidal anti-inflammatory agents (NSAIDs) may cause a decrease in blood levels of the non-aspirin drug.

Administration and Dosage
Osteoarthritis - 100 to 150 mg/day in divided doses (50 mg twice/day or 3 times/ day [diclofenac sodium or potassium] or 75 mg twice/day [diclofenac sodium]). Dosages > 200 mg/day have not been studied.
Rheumatoid arthritis - 150 to 200 mg/day in divided doses (50 mg 3 or 4 times/day [diclofenac sodium or potassium] or 75 mg twice/day [diclofenac sodium]). Dosages > 225 mg/day of the delayed-release diclofenac sodium formulation and dosages > 200 mg/day of immediate-release diclofenac potassium formulation are not recommended.
Ankylosing spondylitis - 100 to 125 mg/day as 25 mg 4 times/day, with an extra 25 mg dose at bedtime, if necessary. Dosages > 125 mg/day have not been studied.
Analgesia and primary dysmenorrhea (diclofenac potassium only) - Recommended starting dose is 50 mg 3 times/day. In some patients, an initial dose of 100 mg followed by 50 mg doses will provide better relief. After the first day, when the maximum recommended dose may be 200 mg, the total daily dose should generally not exceed 150 mg.
ARTHRITIS

RISK FACTORS FOR OSTEOPOROSIS DEVELOPMENT
A number of factors may predispose a person to developing osteoporosis. Some risk factors, unfortunately, cannot be lessened by choices in behavior. They include the following:
- Gender. Chances of developing osteoporosis are greater if you are a woman. Women have less bone tissue and lose bone more rapidly than men because of the hormonal changes resulting from menopause.
- Age. The older you are, the greater your risk of osteoporosis. Your bones become less dense and weaker as you age.
- Body size. Small, thin-boned women are at greater risk.
- Ethnicity. Caucasian and Asian women are at highest risk; African American and Latino women have a lower but significant risk.
- Family history. Susceptibility to fracture may be, in part, hereditary. People whose parents have a history of fractures also seem to have reduced bone mass and may be at risk for fractures.
Several risk factors can be changed by choices in lifestyle behaviors, medication, and diet. They include the following:
- Levels of sex hormones - abnormal absence of menstrual periods (amenorrhea), low estrogen level (menopause), and low testosterone level in men may signal potential problems
- Anorexia
- A lifetime diet low in calcium and vitamin D
- Use of certain medications, such as glucocorticoids or some anticonvulsants
- An inactive lifestyle or extended bed rest
- Cigarette smoking
- Excessive use of alcohol
*5/277/5*
HEALTHY BONES

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