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Generic Vibra-tab (Doxycycline 100mg)
- Denomination
Vibramycin
- Active Substance
Doxycycline
- Indications for Use.
Infectious-inflammatory diseases provoked by the microorganisms sensitive to the drug, which include: pneumonia, bronchitis, empyema, angina, cholecystitis, pyelonephritis, endometritis, prostatitis, syphilis, gonorrhea, whooping cough, brucellosis, rickettsiosis, purulent infections of soft tissues, osteomyelitis.
- Action
Pluripotential bacteriostatic antibiotic. It penetrates inside a cell and operates upon intracellularly placed causative agents.
- Posology and Administration
Posology and administration of Doxycycline are done strictly individually with compliance of diagnosis and the stage of disease, the treatment is done under a medical control.
Adults orally or (intravenous drip-feed) are administered 200 mg/daily in the 1-st day of the treatment. Further day’s administration is 100-200 mg/daily depending on the severity of clinical course of the disease. Repetition factor of intake is 1-2 times/daily. In children of more than 8 years of age and with the body mass of more than 50 kg a daily dose to be taken by mouth or to be introduced intravenously (drip-feed) is 4 mg/kg in the first day of the treatment. Further day’s administration is 2-4 mg/kg/daily depending on the severity of clinical course of the disease. Repetition factor of oral intake (or intravenous introduction) is 1-2 times/daily. Recommended minimal time for (intravenous drip-feed) 100 mg of the drug (at concentration of infusion solution of 0.5 mg/ml) is 1 hour.
In uncomplicated gonorrhea and syphilis Doxycycline is used on regular schemes.
- Counterindications
Pregnancy (second half), childhood (less than 8 years of age). Hypersensitivity, porphyria, severe liver failure, lessen number of leukocytes in blood.
- Should Be Taken with Precautions, if…
In a long-term Doxycycline care one should analyze the blood picture of liver and kidney discharges.
In the process of treatment during 4-5 days after - it is counterindicated a direct exposure to the sun light or UV rays.
In the period of treatment alcohol consumption should be excluded.
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Interface with Other Medications
If Doxycycline is used together with other medications you need to take opinion of your doctor.
- Overdosing
There is no information concerning acute Doxycycline poisoning. In cases of overdosage and emergence of some sort of complaints it is necessary to stop the drug intake immediately and seek medical assistance at the nearest hospital.
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Side Effects
Possible – nausea, vomiting, loss of appetite, pains in the stomach, diarrhea, constipation, allergic reactions (skin rash, itching). In long-term use of the drug – disorders of the blood composition, compromised liver function, and sensitivity to ultraviolet are possible. Persistent change of tooth enamel color.
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Pregnancy and Lactation
Doxycycline may be used in pregnancy only in cases when its application for the mother is absolutely justified, and the use of a safer alternative drug is either impossible or counterindicated. In the period of Doxycycline therapy breast-feeding should be stopped.
- Driving
There are no data on negative influence of the drug on the ability to drive vehicles or operate machinery.
SCOPE OF THE PHYSICAL ACTIVITY DEFICIENCY PROBLEM
An Independent Risk Factor
Sedentary behavior is an independent risk factor for increased incidence and progression of chronic health conditions (CHCs). It is also an independent risk factor for increased mortality from CHCs. In fact, the majority of U.S. deaths are now from CHCs.
- 7 of 10 deaths (1.7 million of 2.4 million deaths) in the U.S. in 1999 were due to CHCs.
- U.S. data 1987-1990 show that there were 1.6 million deaths from chronic diseases, which represented 24.3 million years lost, with an average of 14.8 years lost per death.
- No regular exercise accounted for 256,686 deaths from CHCs according to 1986 data and these deaths constituted about 12 % of the total 2.1 million deaths that occurred in 1986:
205,254 deaths from coronary heart disease (35% of these deaths)
43,063 deaths from stroke (29% of these deaths)
8369 deaths from colon cancer (15% of these deaths)
Deaths from type 2 diabetes were not determined in this study.
- As the U.S. population grew 17% from 1986 to 2000, the adjusted premature number of deaths from no regular exercise is 300,000 (excluding diabetes, as the 1986 report did not include it).
Sedentary Lifestyle and Premature Death
Sedentary lifestyle accounted for 334,144 premature deaths in the U.S. from CHCs, according to our estimates, which are based on numbers of deaths reported on the American Heart Association, American Diabetes Association, and American Cancer Society web sites. Percentage reductions of deaths were taken from the percentage of prevalence when physically inactive populations were compared to moderately physically active populations in the literature.
The number of deaths from sedentary living is three times greater than that from microbial agents and also exceeds all deaths from firearms, illicit usage of drugs, sexually transmitted diseases, and motor vehicle accidents. The number of deaths due to physical inactivity (334,000 annual premature deaths in the U.S.) trails tobacco (430,000), but exceeds obesity (300,000). Thus, a major cause of death in the U.S. is sedentary living. Physical inactivity is one of the top two causes of all-cause mortality in the U.S. today, and directly contributes to the current third-highest death rate in the country, which is obesity.
In the last 100 years, the leading causes of death have dramatically shifted from the scourge of infectious diseases (in 1900), to cardiovascular diseases, obesity, and type 2 diabetes mellitus (in 2000) - all of which are directly associated with sedentary living. In essence, physical inactivity constitutes the new scourge for humanity. Some site-specific cancers, such as colon cancer, are also associated with sedentary lifestyle.
*2/282/5*
GENERAL HEALTH
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A. Refund Policy
Q. Can you tell me if I should be taking Generic Vibra-tab ( Doxycycline 100mg ) ? Or, will it work for me?
A. We cannot advise you in any capacity in this matter. You should not take any medication without consulting a physician first.
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A. By law, we regret that we are unable to accept returned pharmaceuticals. If your purchase is defective in any way, we will be pleased to replace it at no cost to you.
Q. What about importing of Generic Vibra-tab ( Doxycycline 100mg ) to my country ?
A. Importation of prescription medication is legal in most countries (including the US, UK, France, Spain, Hong Kong, Japan and S. Korea) provided the medication is for personal use and is not a controlled substance. If you are in doubt about the situation in your country, check with your local Post Office.
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