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Generic Verelan sr (Verapamil 120/240mg)
- Denomination
Calan, Isoptin
- Active Substance
Verapamil
- Indications for Use.
Treatment and prevention of heart rhythm disorder
paroxysmal supraventricular tachycardia;
atrial flutter and twinkle (tachi-arrhythmic variant);
superventricular beats.
Treatment and preventive measures of:
chronic stable angina (angina of effort);
unstable angina (rest angina);
vasospastic stenocardia (Prinzmetal’s angina, variant angina pectoris).
Treatment of arterial hypertension.
- Action
Verapamil has anti-arrythmic, anti-anginal and hypotensive value,
invokes distention of coronary vessels and increases coronary blood flow, reduces myocardium’s need in oxygen.
- Posology and Administration
Verapamil’s dose should be chosen individually, in relation to the patient’s condition, severity level, distinctions of the course of disease and efficiency of the therapy. The drug is administered 40-80 mg 3 times a day, when there is stenocardia and supraventricular tachycardia in 3 intakes, when there is arterial hypertension in 2 intakes, a daily dose when there is arterial hypertension may be up to 320 mg. When there is a long-time therapy a daily dose should not exceed 480 mg. Overdosage is possible but for a very short time and under thorough medical control.
In compromised liver function patients excretion of Verapamil from the body is slow; therefore the treatment is advisable to start from minimal doses. A daily dose of the drug should not exceed 120 mg.
- Counterindications
Evidenced bradycardia, SSS, cardiogenic shock, AV block of the II-III degree, WPW syndrome, and low arterial tension, chronic heart failure of II B-III stage, acute heart failure and hypersensitivity to Verapamil.
- Should Be Taken with Precautions, if…
While treatment a control of the function of cardio-vascular and respiration systems is needed, likewise a control of blood picture, volume of blood circulation and quantity of excreted urine.
Abrupt withdrawal of treatment is not recommended.
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Interface with Other Medications
The use of the drug and/or its combination with any medication is possible only on a doctor’s order. Consult your attending doctor if you take other medicines.
- Overdosing
Symptoms: bradycardia, evidenced drop of arterial tension, heart failure, shock, cessation of heart performance.
- Side Effects
Verapamil may provoke dizziness, headache, flushing, nausea and constipations. In rare cases there are registered nervousness, retardation, fatigability, allergic reactions (skin itching, rash), dysfunction of blood formation, and, as a consequence, compositional disorder of blood. When big doses of Verapamil are applied, especially in liable patients, evidenced drop of arterial tension and emergence of heart failure are possible.
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Pregnancy and Lactation
The use of Verapamil in pregnant and breastfeeding women is justified only in the cases when a supposed favor exceeds a possible negative influence to the fetus or baby.
- Driving
Until you have not found out how you respond to this drug do not get behind a wheel, likewise do not do other activities which require alertness.
BLOOD PRESSURE: HYPOTENSION AND HYPERTENSION
Low blood pressure-hypotension
People with blood pressure somewhat below the average used to be said to suffer from low blood pressure. The condition was called hypotension. Now records are available of great numbers of people with somewhat lower blood pressures who nevertheless feel quite well, and who seem to be likely to live long. Hypotension is recognized as a condition in which the systolic pressure is under 80 mm. of mercury or 20 mm. below the usual average of the person concerned. The blood pressure may be quite low after prolonged rest in bed or with malnutrition. The blood pressure may also be lowered by conditions affecting the spinal cord or by the operation which cuts off the sympathetic nervous system.
A feeling of faintness or weakness may be the only indication that the blood pressure is lower than it should be.
High blood pressure-hypertension
High blood pressure, or hypertension, is diagnosed by the doctor when, after repeated examination, the pressure is found to be above the average for healthy young people in the area in which the person lives. In the United States, levels are around 120 to 140 systolic and 80 to 90 diastolic. The pressure may reach 180 systolic and 100 diastolic without the appearance of any symptoms.
If the person suffers with acute hypertension, such symptoms as convulsions, loss of vision, severe headaches and kidney inflammations may be indications. In chronic high blood pressure dizziness, headaches, hemorrhages in the eye or the brain, heart failure and uremia may be present. Still, cases are known in which people with definitely high blood pressures on measurement have failed to manifest any of these symptoms.
Associated with high blood pressure the doctor may find disturbances of the function of the kidneys; disturbances of function of the adrenal glands; or in some instances, apparently no immediate cause except some psychological problem. When a cause cannot be found the case is called "essential hypertension." Often the first indication of the condition may be changes in the blood vessels at the back of the eye, which the doctor sees with an ophthalmoscope. Definite relationships have been established between the blood-flow through the kidneys and the pressure of high blood pressure. A high salt or sodium chloride intake may set up high blood pressure. The kidney condition is believed to indicate some substances are elaborated by the kidney which may establish high blood pressure. The pressure with high salt intake is associated with the functioning of the adrenal glands.
In an examination of the patient with high blood pressure study of the urine, which indicates the condition of the kidneys, is important. A low specific gravity - under 1020 - and the presence of albumin or pus may show that the kidney condition is responsible. If the kidney function, as determined by a variety of tests, is normal, the doctor then sees if the adrenal activity is proper. A number of laboratory and functional tests are available which the doctor can use.
Wise physicians recommend that patients be reassured and do not disturb themselves about the pressure, in the absence of severe symptoms and in failure to find anything wrong about the blood vessels of the retina of the eye, the heart size and action and the kidney function. If the patient has vague symptoms and sound organs, suggests Dr. William Dock, search should be made for sources of anxiety and frustration. The facts ascertained by the doctor in his study determine the nature of the treatment that may be prescribed.
The suggestion has been made that the first steps are: reassurance of the patient, sedation with the appropriate drags and restricted use of salt. Rigid elimination of salt from the diet is recommended when there is headache, dizziness, and heart failure. Several drags are known which will lower blood pressure but all are difficult to use and must be prescribed by the doctor for the individual patient. The operation called "sympathectomy" is tried when the condition cannot be controlled but always with a recognition that it may have after-effects with annoying symptoms and disability.
Weight reduction, adequate rest, suitable mental hygiene, are among the best measures that can be recommended in a majority of cases of high blood pressure.
*2/318/5*
CARDIO & BLOOD
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