Generic Theox Cr

1. Denomination

Aerolate, Theo-24

2. Active Substance

Theophylline

3. Indications for Use.

Bronchial asthma
Symptomatic treatment of bronchospasm of various etiologies
Lung hypertension
Chained-Stokes respiration failure
Night apnea, migraine
Stroke

4. Action

Theophylline enlarges bronchi, blood vessels, mainly the vessels of brain, skin and kidneys. The drug decreases lung vessel resistance and tension in lesser circulation.
Theophylline takes spasmolytic effect to peripheral veins, increases renal blood flow; it takes a moderately manifested urinative effect.
Theophylline takes stimulating effect on respiration center; it enhances heart rate and heart force.

5. Posology and Administration

Posology and administration are to be set up individually. An average starting dose is 400 mg /daily. Upon condition of good tolerance a dose may be increased approximately by 25% from the starting one every 2-3 days up to attainment of the optimal therapeutic effect. Maximal daily doses which may be applied without a control of blood concentration are: children of 1-9 years of age — 24 mg/kg, 9-12 years of age — 20 mg/kg, 12-16 years of age — 18 mg/kg; patients of 16 years of age and older — 13 mg/kg or 900 mg/daily.

6. Counterindications

Age under three years, hypersensitivity to Theophylline, epilepsy, increased readiness for convulsions, gastric and duodenal ulcer.

7. Should Be Taken with Precautions, if…

With caution it should be used in severe stenocardia, in acute periods of myocardial infarction and heart failure. Likewise caution is needed in evidenced compromised liver and kidney function, during pregnancy and lactation. In severe diseases of cardio-vascular system, also in elderly patients a Theophylline dose should be decreased.

8. Interface with Other Medications

Do not try shots of self-administration (especially of combination of drugs) of medications without a doctor’s assistance.

9. Overdosing

Symptoms: strong emotional excitement, accompanied with a feeling of anxiety and fear, confusion of consciousness, convulsions, tachycardia, arrhythmia, low arterial tension, nausea, diarrhea, vomiting with bloody tap. Diabetes, pains in muscles, muscle weakness.

10. Side Effects

Irritation of mucus coating of the stomach, nausea, agitation, insomnia, tachycardia, arrhythmias, low arterial tension. Side effects will decrease when a Theophylline dose decreases.

11. Pregnancy and Lactation

Theophylline therapy during pregnancy is possible only in the cases when a supposed therapy effect exceeds a potential risk for the fetus, provided there is no alternative reliable therapy. During the treatment breast-feeding should be cancelled.

12. Driving

Before you start the activities which require alertness see how your body responds to Theophylline.

UNDERSTANDING ALLERGY: ALLERGIC RESPONSES
In the case of skin allergies, local warmth and flushing may be caused when the circular muscles in the walls of the arteries that bring the blood to the area are relaxed (dilated), and allowing an increased flow of warm blood into the tissues supplied by the dilated arteries. The skin is pale, becomes cold, and may even get numb and blue when the circular muscles contract and the vessels are constricted, reducing the local blood supply. Reynaud's disease is a form of allergic arterial blood vessel spasm that restricts the flow of blood to the limbs and changes in their temperature and color.
Another primary allergic response is over-activity of the mucus-secreting glands in the allergically reacting areas of the body. Increased nasal, postnasal, and eye mucus are noted in cases of allergic sinusitis, chronic rhinitis, and hay fever. At times there is so much thick, drying, sticky bronchial mucus secreted during an attack of asthma that this obstructing substance has to be thinned out by medication, intravenous fluids, steam inhalation, and even bronchial irrigation. There are life-threatening instances when the mucus-filled air passages are almost completely blocked and the bronchial tubes have to be irrigated and suctioned as an emergency measure. The large intestines may produce a lot of mucus during a flare-up of colitis or ileitis, and there may be a considerable amount of mucus, at times blood-tinged or grossly bloody, present in the bowel movement.
Wherever an allergic reaction occurs in the body, some or all of the symptoms just described may occur. The site of the allergic congestion, muscle spasm, or increased secretion determines the kind of symptoms that will occur. When the offending substances reach the brain, the reaction might be headache, anger, depression, irritability, restlessness, anxiety, dizziness, confusion, fatigue, or disorientation. Those allergens affecting the digestive tract may cause ulcer symptoms, gallbladder attack, vomiting, indigestion, bloating, cramps, gas, rectal pain or itching, diarrhea, or constipation. Muscles may respond to allergens with soreness, flulike aching, or spasms. And so forth... you needn't be prone to the usual allergies like sniffles, sneezing, itching, and rashes to be a seriously affected individual because, as you can see, many kinds of systemic allergic reactions are hidden far within the body and affect many important internal structures.
*3/295/5*
ANTI-ALLERGIC/ASTHMA

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