Generic Theolair Tr

1. Denomination

Aerolate, Theo-24

2. Active Substance

Theophylline

3. Indications for Use.

Bronchial asthma
Symptomatic treatment of bronchospasm of various etiologies
Lung hypertension
Chained-Stokes respiration failure
Night apnea, migraine
Stroke

4. Action

Theophylline enlarges bronchi, blood vessels, mainly the vessels of brain, skin and kidneys. The drug decreases lung vessel resistance and tension in lesser circulation.
Theophylline takes spasmolytic effect to peripheral veins, increases renal blood flow; it takes a moderately manifested urinative effect.
Theophylline takes stimulating effect on respiration center; it enhances heart rate and heart force.

5. Posology and Administration

Posology and administration are to be set up individually. An average starting dose is 400 mg /daily. Upon condition of good tolerance a dose may be increased approximately by 25% from the starting one every 2-3 days up to attainment of the optimal therapeutic effect. Maximal daily doses which may be applied without a control of blood concentration are: children of 1-9 years of age — 24 mg/kg, 9-12 years of age — 20 mg/kg, 12-16 years of age — 18 mg/kg; patients of 16 years of age and older — 13 mg/kg or 900 mg/daily.

6. Counterindications

Age under three years, hypersensitivity to Theophylline, epilepsy, increased readiness for convulsions, gastric and duodenal ulcer.

7. Should Be Taken with Precautions, if…

With caution it should be used in severe stenocardia, in acute periods of myocardial infarction and heart failure. Likewise caution is needed in evidenced compromised liver and kidney function, during pregnancy and lactation. In severe diseases of cardio-vascular system, also in elderly patients a Theophylline dose should be decreased.

8. Interface with Other Medications

Do not try shots of self-administration (especially of combination of drugs) of medications without a doctor’s assistance.

9. Overdosing

Symptoms: strong emotional excitement, accompanied with a feeling of anxiety and fear, confusion of consciousness, convulsions, tachycardia, arrhythmia, low arterial tension, nausea, diarrhea, vomiting with bloody tap. Diabetes, pains in muscles, muscle weakness.

10. Side Effects

Irritation of mucus coating of the stomach, nausea, agitation, insomnia, tachycardia, arrhythmias, low arterial tension. Side effects will decrease when a Theophylline dose decreases.

11. Pregnancy and Lactation

Theophylline therapy during pregnancy is possible only in the cases when a supposed therapy effect exceeds a potential risk for the fetus, provided there is no alternative reliable therapy. During the treatment breast-feeding should be cancelled.

12. Driving

Before you start the activities which require alertness see how your body responds to Theophylline.

ENTER OF ALLERGEN-CONTAINING PARTICLES
Inhaled airborne particles that are present indoors (dust, dust mites, animal dander, or molds) or outdoors (tree, grass or weed pollens, molds, animal dander, or scales and other tiny parts of insects) can cause internal (systemic) changes in at least three ways.
- They become trapped in the moist, sticky mucus in the nose and throat, and some allergically active substances can dissolve in the moisture and pass through the walls of the membranes lining the upper respiratory tract and soon enter the circulation for body-wide distribution.
- Animal research with radioactive material has demonstrated that some active substances reach the brain directly from the oral cavity by an as-yet-unidentified route.
- Allergen-containing mucus that is swallowed enters the upper part of the digestive system by way of the stomach and undergoes the same processing that ingested foods are subjected to. Eventually the allergically or biologically active components of the digested airborne allergens pass through the walls of the intestines and enter the minute intestinal blood vessels (capillaries), which come together like the tributaries of a river, becoming veins that transport substances from the intestine to the liver for processing by the liver cells. Then blood from the liver goes directly to the heart, which pumps the allergen-containing blood throughout the entire circulatory system. The allergens reach every allergically reactive cell in every organ of the body, and this certainly includes the muscles and joints and nearby structures that are the tissues involved in cases of arthritis.
In addition, the air-polluting chemical fumes present in indoor and outdoor air accompany the atmospheric oxygen we need as it passes through the walls of the capillary blood vessels in the lungs and enters the circulation. Along with our oxygen, these highly reactive fumes reach all the active and potential arthritis sites throughout the entire body.
*2/295/5*
ANTI-ALLERGIC/ASTHMA

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