Generic T-phyl sr (Theophylline 200/300mg)
- Denomination
Aerolate, Theo-24
- Active Substance
Theophylline
- Indications for Use.
Bronchial asthma
Symptomatic treatment of bronchospasm of various etiologies
Lung hypertension
Chained-Stokes respiration failure
Night apnea, migraine
Stroke
- Action
Theophylline enlarges bronchi, blood vessels, mainly the vessels of brain, skin and kidneys. The drug decreases lung vessel resistance and tension in lesser circulation.
Theophylline takes spasmolytic effect to peripheral veins, increases renal blood flow; it takes a moderately manifested urinative effect.
Theophylline takes stimulating effect on respiration center; it enhances heart rate and heart force.
- Posology and Administration
Posology and administration are to be set up individually. An average starting dose is 400 mg /daily. Upon condition of good tolerance a dose may be increased approximately by 25% from the starting one every 2-3 days up to attainment of the optimal therapeutic effect. Maximal daily doses which may be applied without a control of blood concentration are: children of 1-9 years of age — 24 mg/kg, 9-12 years of age — 20 mg/kg, 12-16 years of age — 18 mg/kg; patients of 16 years of age and older — 13 mg/kg or 900 mg/daily.
- Counterindications
Age under three years, hypersensitivity to Theophylline, epilepsy, increased readiness for convulsions, gastric and duodenal ulcer.
- Should Be Taken with Precautions, if…
With caution it should be used in severe stenocardia, in acute periods of myocardial infarction and heart failure. Likewise caution is needed in evidenced compromised liver and kidney function, during pregnancy and lactation. In severe diseases of cardio-vascular system, also in elderly patients a Theophylline dose should be decreased.
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Interface with Other Medications
Do not try shots of self-administration (especially of combination of drugs) of medications without a doctor’s assistance.
- Overdosing
Symptoms: strong emotional excitement, accompanied with a feeling of anxiety and fear, confusion of consciousness, convulsions, tachycardia, arrhythmia, low arterial tension, nausea, diarrhea, vomiting with bloody tap. Diabetes, pains in muscles, muscle weakness.
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Side Effects
Irritation of mucus coating of the stomach, nausea, agitation, insomnia, tachycardia, arrhythmias, low arterial tension. Side effects will decrease when a Theophylline dose decreases.
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Pregnancy and Lactation
Theophylline therapy during pregnancy is possible only in the cases when a supposed therapy effect exceeds a potential risk for the fetus, provided there is no alternative reliable therapy. During the treatment breast-feeding should be cancelled.
- Driving
Before you start the activities which require alertness see how your body responds to Theophylline.
DETERMINING ALLERGIES IN PATIENTS
Since the early days of allergic medicine, solutions - allergenic extracts - have been prepared from animal dander and the hair of horses, cattle, hogs, goats, cats, and stray dogs; other extracts are prepared from various molds and the pollens of many species of trees, grasses, and weeds. During testing for allergies, small amounts of these solutions or extracts were scratched or injected into the outer layer of a patient's skin. If a hive-like wheal or an area of redness developed at the test site, an allergy to the particular animal, mold, or pollen source of the extract was suspected.
The skin reaction at the test area is currently interpreted as objective evidence that the body's misinformed immune system has produced unnecessary specific allergic antibodies to fight off the nonthreatening natural airborne substances. It has incorrectly "recognized" the testing extracts as carriers of the biologically active, supposedly harmful offenders that it tried to dispose of before they caused any adverse effects. Allergic reactions to harmless environmental substances may be viewed as evidence of an overactive immunologic defense mechanism; but it's not quite that simple, and there are exceptions. Most allergy patients were advised to dispose of pets, stay away from animals, move away or stay indoors during the pollen seasons, take desensitizing allergy shots, or simply to live with it with the help of various medications. Skin tests, however, are not as accurate as we allergists would like them to be (food skin tests are generally regarded to be only 20% accurate - an error of 80%!) and they cannot show us which particular symptoms are caused by specific allergic reactions to different offenders.
Many patients who have been told they had no allergies because of negative conventional skin tests, especially for foods and molds, have been shown to be highly sensitive to these allergens when tested by the symptom-duplicating provocative-testing methods employed by clinical ecologists. Dr. Carleton Lee discovered the symptom-relieving/neutralizing technique that often eliminated the symptoms of active allergies within a few minutes. This was a giant step in the diagnosis of internal allergies, because now we could often stop or reduce the intensity of reactions brought on by provocative testing or a presenting illness.
At times some skin tests with highly colored food extracts would leave a small area of food pigment at the test site. The use of sublingual tests eliminated these problems. The thin-walled sublingual veins on the floor of the mouth just under the tip of the tongue in the area behind the lower front teeth are very absorbent and close to the surface. Ecologists Dr. Guy O. Pfeiffer and Dr. Lawrence D. Dickey adopted the needle-free technique of Dr. French Hansel, in which small amounts of carefully measured drops of allergenic extracts are placed under the tongue. Just as a thermometer placed under the tongue accurately and without discomfort registers internal temperature quickly, sublingual tests will often duplicate with great accuracy the various symptoms caused by a patient's allergies. The test materials consist of drops of extracts prepared from frequently eaten foods, common airborne molds, pollens, and the like, and solutions prepared from environmental chemicals that are often encountered in daily living.
Provocative nasal inhalation tests are a very sensitive diagnostic measure that Dr. Harris Hosen suggested. During testing, dry powdered airborne allergens like house dust; animal dander; tree, grass and weed pollens; and various molds are sniffed deeply into the patient's nose. They travel up the tear ducts to the surface of the eyes and to the depths of the bronchial tubes. They often cause diagnostically valuable local symptoms when they contact the allergically sensitive cells in the eyes and respiratory tract. They also induce important symptoms throughout the body after they are absorbed into the circulation from the upper respiratory tract and the intestines.
*7/295/5*
ANTI-ALLERGIC/ASTHMA
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