Generic Renagel (Sevelamer hydrochloride 400/800mg)
DIGESTIVE SYSTEM: ULCERATIVE COLITIS
For acute attacks your doctor may prescribe a rectal corticosteroid enema or foam to be inserted into the rectum at bedtime or twice daily. A corticosteroid reduces inflammation of the intestinal wall and brings the symptoms under control Administering a corticosteroid directly into the bowel avoids some of the adverse effects such as moon face, thinning of die skin and weight gain that can occur with a corticosteroid taken by mouth for long periods. Treatment is usually limited to three- or four-week courses, so the corticosteroid does not cause unwanted effects throughout the body (systemically). Some absorption can occur With prolonged treatment, should this prove necessary, and then you may need additional doses of a corticosteroid in times of major stress, such as surgery. Liquid and foam preparations are equally effective. Foam products are easier to use and more convenient, especially if you have difficulty retaining a liquid enema. Suppositories are prescribed for proctitis.
Sometimes it may be necessary to take the corticosteroid prednisolone by mouth. Your doctor should prescribe ordinary prednisolone tablets, not the red or brown enteric-coated type (brand name Deltacortril Enteric) as these act slowly and are less effective in diarrhocal diseases. A corticosteroid is not taken all the time and the dose will be tapered off gradually once the disease is under control. In acute flare-ups you may need to be admitted to hospital.
Sulphasalazine (brand name Salaaopyrin) or one of the newer related drugs, mesalaziot (Asacol; Pentasa) or olsalazine (Dipentum) also reduce inflammation. They are widely used to prevent relapse and may also be used for treating mild ulcerative colitis. Each of these medicines has its own pattern of unwanted effects and the newer preparations often cause diarrhoea which can be confused with an exacerbation of the underlying disease.
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General health
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