Generic Lithotabs (Lithium 300mg)
- Denomination
Lithobid
- Active Substance
Lithium Carbonate
- Indications for Use.
Manic and hypomanic states of various genesis, affective psychosis (manic-depressive psychosis, schizoactive one), alcoholism (affective disorders); migraine, Meniere’s syndrome, sexual disturbances, drug dependence (some forms).
- Action
The drug normalizes mental state, not provoking systemic retardation; likewise it takes anti-depressive, sedative and anti-manic effect and benefits in migraine.
- Posology and Administration
The drug is to be taken orally (in 3-4 intakes, the last time before sleep), after meal, the starting dose is 0.6-0.9 g/daily with consequent increase up to 1.2 g/daily, then the dose is to be increased on a daily basis up to 0.3 g to attend a daily dose of 1.5-2.1 g; the maximal daily dose is 2.4 g., in the period of adjustment of therapy the concentration Li+ in plasma should be not less than 0.6 and not higher than 1.2-1.6 mmol/l. In the doses higher than 2 g/daily - time duration of the treatment should be 1-2 weeks. After manic symptoms and signs have disappeared a daily dose is to be gradually decreased to a prevention one (0.6-1.2 g). If after the decrease of the dose manic signs appear anew, the dose is to be increased. In acute manic state the therapeutic concentration of Li+ in blood should be 0.8-1.2 mmol/l, in supporting treatment it should be 0.4-0.8 mmol/l; if concentration Li+ exceeds 1.2 mmol/l, a daily dose should be reduced. A positive result of a preventive monotherapy is evident in case a stable concentration in blood of adults within the limit of 0.4-0.8 mmol/l is maintained not less than 6 months, whereas for children in a dose which allows to maintain therapeutic concentrations within a limit of 0.5-1 mmol/l.
- Counterindications
Hypersensitivity, severe surgery interventions, kidney and/or liver diseases, severe cardio-vascular diseases, pregnancy, breastfeeding, the drug should not be used in children less than 12 years of age.
- Should Be Taken with Precautions, if…
Cardiovascular diseases (including AV blockade, intraventricular block), diseases of central nervous system (epilepsy, Parkinsonism), diabetes, hormonal disturbance, disturbance of the function of endocrine system, infection, psoriasis, kidney failure, stanguria, disturbance water-electrolytic metabolism (salt-free diet, water retention, vomiting, diarrhea).
In the period of treatment alcohol consumption is prohibited.
-
Interface with Other Medications
On the questions of concurrent use of other medications during Lithium Carbonate therapy see your attending doctor.
- Overdosing
Speech disturbance, rhythmic strain and muscle activity, tonic and epileptic convulsions, evolvement of very small quantity of urine, loss of consciousness, terminal state, coma.
- Side Effects
Diarrhea, nausea, vomiting, dry mouth, polyuria, dysfunction of kidneys, disorders of cardiac rhythm, retardation of blood formation and activity of thyroid gland, weak trembling of hands, drowsiness, loss of head’s hair, pimples.
During Lithium Carbonate therapy temporary increase of the body mass and bronchocele formation are possible.
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Pregnancy and Lactation
It is not recommended during pregnancy; during the therapy breastfeeding should be stopped.
- Driving
In the period of treatment caution should be taken in vehicle driving and in involving of other potentially hazardous activities, requiring alertness and responsiveness.
SLEEP: THE GREAT RESTORER
Sleep serves at least two biological purposes in the body: conservation of energy so that we are rested and ready to perform during high-performance daylight hours, and restoration so that neurotransmitters that have been depleted during waking hours can be replenished. This process clears the brain of daily minutiae as a means of preparing for a new day. Getting enough sleep to feel ready to meet daily challenges is a key factor in maintaining optimal physical and psychosocial health.
All of us can identify with that tired, listless feeling caused by sleep deprivation during periods of high stress. Either we can't find enough hours in the day for sleep, or once we get into bed, we can't fall asleep or stay asleep. Insomnia - difficulty in falling asleep quickly, frequent arousals during sleep, or early morning awakening. Insomnia is more common among women than among men, and its prevalence is correlated with age and low socioeconomic status.
Some people have difficulty getting a good night's rest due to other sleep disorders. Sleep apnea, a condition in which a person may experience hundreds of episodes of breathing stoppage during a normal night's sleep, is increasingly common. Typically caused by upper respiratory tract problems in which weak muscle tone allows part of the airway to collapse, sleep apnea results in poor air exchange. This in turn causes a rise in blood pressure and low oxygen supply in the blood. Sleep apnea may do more than just disrupt sleeping cycles; in some cases, it can actually pose a serious health risk.
How much sleep each of us needs to feel refreshed depends on many factors. There is a genetically based need for sleep, different for each species. Sleep duration is also controlled by circadian rhythms, which are linked to the hormone melatonin. People may also control sleep patterns by staying up late, drinking coffee, getting lots of physical exercise, eating a heavy meal, or using alarm clocks. The most important period of sleep, known as the time of rapid eye movement, or REM, sleep, is essential to feeling rested and refreshed by sleep. This is the period of deepest sleep, during which we dream. If we miss this period of sleep, then we are left feeling groggy and sleep deprived.
Though many people turn to over-the-counter sleeping pills, barbiturates, or tranquilizers to get some sleep, the following methods for conquering sleeplessness are less harmful:
- If your sleeplessness arises from worry or grief, try to correct what's bothering you. If you can't correct it yourself, confide in a friend, join a support group, or find a qualified counselor to help you.
- Don't drink alcohol or smoke before bedtime. Alcohol can disrupt sleep patterns and make insomnia worse. Nicotine also makes you wakeful.
- Avoid eating a heavy meal in the evening, particularly at bedtime. Don't drink large amounts of liquids before retiring, either.
- Eliminate or reduce consumption of caffeinated beverages except in the morning or early afternoon.
- Try a mid-afternoon nap, when circadian rhythms make you especially sleepy. But avoid taking multiple catnaps - a practice that will keep you awake at night when you should be sleeping.
- Spend an hour or more relaxing before retiring. Read, listen to music, watch TV, or take a warm bath.
- If you're unable to fall asleep, get up and do something rather than lie there. Don't bring work to bed. If you wake up in the middle of the night and can't fall asleep again, try reading for a short time. Counting sheep or reconstructing a happy event or narrative in your mind may lull you to sleep.
- Avoid reproaching yourself. Don't make your sleeplessness a cause for additional worry. Insomnia is not a crime. Not everyone needs eight hours of sleep. You can feel well - and be quite healthy - on less.
- Don't worry that you have to make up lost sleep. One good night's sleep will reinvigorate you.
- Don't watch the clock at night. Turn it to the wall to avoid the temptation to worry about the night slipping away.
- Go to bed and rise on a regular schedule. Keep this schedule no matter how much you have or haven't slept in the recent past.
- Get daily exercise, but not within three hours of bedtime.
- Experiment. . . Figure out how much sleep you need to feel good, and then schedule it.
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ANTI-DEPRESSANT
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Q. Can you tell me if I should be taking Generic Lithotabs ( Lithium 300mg ) ? Or, will it work for me?
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