Generic Isoptin Sr

1. Denomination

Calan, Isoptin

2. Active Substance

Verapamil

3. Indications for Use.

Treatment and prevention of heart rhythm disorder
paroxysmal supraventricular tachycardia;
atrial flutter and twinkle (tachi-arrhythmic variant);
superventricular beats.
Treatment and preventive measures of:
chronic stable angina (angina of effort);
unstable angina (rest angina);
vasospastic stenocardia (Prinzmetal’s angina, variant angina pectoris).
Treatment of arterial hypertension.

4. Action

Verapamil has anti-arrythmic, anti-anginal and hypotensive value,
invokes distention of coronary vessels and increases coronary blood flow, reduces myocardium’s need in oxygen.

5. Posology and Administration

Verapamil’s dose should be chosen individually, in relation to the patient’s condition, severity level, distinctions of the course of disease and efficiency of the therapy. The drug is administered 40-80 mg 3 times a day, when there is stenocardia and supraventricular tachycardia in 3 intakes, when there is arterial hypertension in 2 intakes, a daily dose when there is arterial hypertension may be up to 320 mg. When there is a long-time therapy a daily dose should not exceed 480 mg. Overdosage is possible but for a very short time and under thorough medical control.
In compromised liver function patients excretion of Verapamil from the body is slow; therefore the treatment is advisable to start from minimal doses. A daily dose of the drug should not exceed 120 mg.

6. Counterindications

Evidenced bradycardia, SSS, cardiogenic shock, AV block of the II-III degree, WPW syndrome, and low arterial tension, chronic heart failure of II B-III stage, acute heart failure and hypersensitivity to Verapamil.

7. Should Be Taken with Precautions, if…

While treatment a control of the function of cardio-vascular and respiration systems is needed, likewise a control of blood picture, volume of blood circulation and quantity of excreted urine.
Abrupt withdrawal of treatment is not recommended.

8. Interface with Other Medications

The use of the drug and/or its combination with any medication is possible only on a doctor’s order. Consult your attending doctor if you take other medicines.

9. Overdosing

Symptoms: bradycardia, evidenced drop of arterial tension, heart failure, shock, cessation of heart performance.

10. Side Effects

Verapamil may provoke dizziness, headache, flushing, nausea and constipations. In rare cases there are registered nervousness, retardation, fatigability, allergic reactions (skin itching, rash), dysfunction of blood formation, and, as a consequence, compositional disorder of blood. When big doses of Verapamil are applied, especially in liable patients, evidenced drop of arterial tension and emergence of heart failure are possible.

11. Pregnancy and Lactation

The use of Verapamil in pregnant and breastfeeding women is justified only in the cases when a supposed favor exceeds a possible negative influence to the fetus or baby.

12. Driving

Until you have not found out how you respond to this drug do not get behind a wheel, likewise do not do other activities which require alertness.

CORONARY DISEASE - DIFFERENT NAMES
Whenever we talk about heart disease, remember we are mostly referring to the disease which is caused by the accumulation of fat and cholesterol in the arteries (blood carrying tubes in the walls of the heart). It accounts for more than 95% of the heart ailments. This means that out of 10 patients with heart ailments more than nine will have obstruction in the blood flow to the muscles of the heart.
This disease of blockage of the heart arteries is medically called 'coronary heart disease (CHD)'. Over the years the same disease has been referred to by different names. The most common of these names is 'angina'. Angina means a pain on the left side of the chest often radiating to the left arm. Since this pain is commonly found in 80% of the people having coronary heart disease, angina also became a common name.
It is known that many patients of CHD do not have a typical chest pain but have shoulder pain, breathlessness, choking sensation or burning sensation in the middle of the chest. These are also due to blockage. So, we must know that CHD can occur without angina pain.
A little less known name of the same disease is 'ischaemia' - (shortage of oxygen). All the problems of the CHD occur due to shortage of oxygen (of course due to the blockage in the tubes supplying blood to the heart muscles). 'Ischaemia' is a more scientific term. CHD is also referred to as the ischaemic heart disease or IHD, and is still being used by many doctors and patients.
Another name of the disease is coronary artery disease (CAD), which is a more appropriate name and is now gaining popularity with doctors and cardiologists.
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CARDIO & BLOOD

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