Generic GlucovanceGlyburide(glibenclamide)-metformin 2.5mg + 400/5mg + 500mg |
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Generic Glucovance (Glyburide(glibenclamide)-metformin 2.5mg + 400/5mg + 500mg)
Glucovance
Glyburide
Type 2 sugar diabetes in adults: in the capacity of the second line preparation in cases of inefficiency of diet therapy, physical exercises and the previous therapy, for the substitution of the previous therapy in patients with stable and well controlled level of glycemia.
Glyburide deflates the level of glucose in blood serum, decreases the absorption of carbohydrates in the digestive tract, likewise the level of total cholesterol.
Glyburide should be taken orally during meal. The drug’s dose should be selected by a doctor individually for each patient according to the level of glycemia. Usually the starting dose is 1 tablet of Glyburide 500/2,5 mg a day. The maximal daily dose is 4 tablets of Glyburide 500/2,5 mg or 2 tablets of Glyburide 500/5 mg.
Hypersensitivity, kidney failure or compromised kidney function, severe infection, the acute and chronic diseases accompanied with hypoxypathy: heart or respiratory failure, recent myocardial infarction, porphyria, pregnancy, the period of breastfeeding, infectious diseases, major surgeries, traumas, major burns and other state which require insulin therapy, compromised liver function, chronic alcoholism, acute alcoholic intoxication.
Care should be taken while using Glyburide in:
While combining the administration of drugs, see your doctor beforehand, ask whether it is possible a combined administration of those medications.
In case if there emerge vomiting, pains in the stomach, which are accompanied with muscle convulsions or general misery stop Glyburide administration and see you doctor immediately.
Nausea, vomiting, pains in the stomach are frequent symptoms in the beginning of therapy and in most cases disappear by itself and do not require a special treatment. As preventive measures for the progression of the mentioned symptoms it is recommended to take Glyburide in 2 or 3 intakes; a slow increase of the drug’s dose also improves its tolerance; likewise “metallic” after-taste in the mouth, allergic reactions, anemia.
Glyburide is counterindicated in pregnancy. During the treatment breastfeeding should be stopped (there are no data on the drug’s ability to excrete into breast milk).
In the period of treatment car driving or other types of activities which require alertness and rapidity of action are not recommended.
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