Generic Diltia Cd

DILTIAZEM HCI
Tablets: 30, 60, 90 and 120 mg (Rx) Various, Cardizem (Marion Merrell Dow)
Capsules, sustained-release: 60, 90, 120, Various, Cardizem SR (Marion Merrell Dow)
180, 240, 300 and 360 mg (Rx) Cardizem CD (Marion Merrell Dow),
Dilacor XR (Rhone-Poulenc Rorer), Tiazac (Forest)
Injections: 25 mg (5 mg/50 mL),
50 mg (5 mg/mL) (Rx) Cardizem (Marion Merrell Dow)

Oral-
Tablets: Start with 30 mg 4 times/day before meals and at bedtime; gradually increase dosage to 180 to 360 mg (given in divided doses 3 or 4 times/day) at 1-to 2-day intervals until optimum response is obtained.
Sustained release:
Cardizem SR -Start with 60 to 120 mg twice daily. Adjust dosage when maximum antihypertensive effect is achieved (usually by 14 days chronic therapy). Optimum dosage range is 240 to 360 mg/day, but some patients may respond to lower doses.
Cardizem CD -
Hypertension: 180 to 240 mg once daily; some patients may respond to lower doses. Maximum antihypertensive effect is usually achieved by 14 days chronic therapy; therefore, adjust dosage accordingly. Usual range is 240 to 360 mg once daily; experience with doses > 360 mg is limited.
Angina: Start with 120 or 180 mg once daily. Some patients may respond to higher doses of up to 480 mg once daily. When necessary, titration may be carried out over a 7- to 14-day period.
Cardizem CD may be opened and administered, but do not crush.
Dilacor XR -
Hypertension: 180 to 240 mg once daily; adjust dose as needed. Individual patients, particularly those > 60 years of age, may respond to a lower dose of 120 mg. Usual range is 180 to 480 mg once daily. Although current clinical experience with the 540 mg dose is limited, the dose may be increased to 540 mg with little or no increased risk of adverse reactions. Do not exceed 540 mg once daily. Angina: Adjust dosage to each patient's needs, starting with a dose of 120 mg once daily, which may be titrated to doses of up to 480 mg once daily, when necessary, titration may be carried out over a 7- to 14-day period.
Hypertensive or anginal patients treated with other formulations of diltiazem can safely be switched to Dilacor XR at the nearest equivalent total daily dose. However, subsequent titration to higher or lower doses may be necessary and should be initiated as clinically indicated.
Administration in the morning on an empty stomach is recommended.
Parenteral -
Direct IV single injections (bolus): The initial dose is 0.25 mg/kg as a bolus administered over 2 minutes (20 mg is a reasonable dose for the average patient). If response is inadequate, a second dose may be administered after 15 minutes. The second bolus dose should be 0.35 mg/kg administered over 2 minutes (25 mg is a reasonable dose for the average patient). Individualize subsequent IV bolus doses. Dose patients with low body weights on a mg/kg basis. Some patients may respond to an initial dose of 0.15 mg/kg, although duration of action may be shorter.
Continuous IV infusion: For continued reduction of the heart rate (up to 24 hours) in patients with atrial fibrillation or atrial flutter, an IV infusion may be administered. Immediately following bolus administration of 20 mg (0.25 mg/kg) or 25 mg (0.35 mg/kg) and reduction of heart rate, begin an IV infusion. The recommended initial infusion rate is 10 mg/hr. Some patients may maintain response to an initial rate of 5 mg/hr. The infusion rate may be increased in 5 mg/hr increments up to 15 mg/hr as needed, if further reduction in heart rate is required. The infusion may be maintained for up to 24 hours. Therefore, infusion duration > 24 hours and infusion rates > 15 mg/hr arc not recommended.
Concomitant therapy: Concomitant therapy with p-blockers or digitalis is usually well tolerated, but the effects of co-administration cannot be predicted, especially in patients with left ventricular dysfunction or cardiac conduction abnormalities. Use caution in titrating dosages for impaired renal or hepatic function patients, since dosage requirements are not available.
CARDIO & BLOOD – CHOLESTEROL

TRUTH ABOUT CHOLESTEROL: HEART-SAVING DIET IN A NUTSHELL

• Don't eat too much carbohydrate.
Grains, sugar and starches promote high cholesterol, weight gain and make you more likely to develop diabetes. If you are at risk of heart disease you will need to avoid sugar and strictly limit your intake of bread, pasta, rice, breakfast cereals, potatoes, rice, bananas and all foods containing flour.

• Avoid trans fatty acids.
These are labeled on foods as "hydrogenated vegetable oil", "partially hydrogenated vegetable oil" or "vegetable fat". These are man made, chemically altered fats that are formed when a liquid vegetable oil is turned into a solid, such as in margarine. They are also present in many cooking oils that have been extracted using heat. Trans fats raise LDL "bad" cholesterol, lower HDL "good" cholesterol and promote inflammation in your body. They promote the development of insulin resistance (Syndrome X), and in this way make you fat. The best fats to eat are those labeled "cold pressed" or "extra virgin", as well as virgin coconut fat, butter and ghee. Saturated fats are not as bad for you as the media claim. Foods such as eggs, red meat and butter have been part of the human diet for many generations, at a time when heart disease was rare. Moderate amounts of saturated fat in the diet are not a problem in healthy individuals. There are many cases of vegans, who eat no animal products yet have high cholesterol.

• Don't smoke cigarettes.
Hundreds of toxic chemicals are present in cigarettes which inflame and damage the artery walls. This promotes high blood pressure and the development of fatty deposits on the artery walls. Cigarettes are a major source of free radicals, contributing to inflammation in the body. Nicotine stimulates the production of adrenaline, which increases your heart rate and blood pressure.

• Look after your liver.
The liver is the major site of cholesterol production, therefore if it is kept healthy; you should not have a cholesterol problem. Approximately 20 percent of Australians have a fatty liver, whereby fatty tissue replaces normal liver cells, severely compromising liver function. Unless you work on improving your liver function, you will not be able to achieve a healthy cholesterol level.

• Eat good fats.
Monounsaturated and polyunsaturated fats help to keep your cholesterol levels in check. Suitable foods to include in your diet are olive oil, avocados and raw nuts and seeds. Omega 3 fats are especially beneficial for the heart, and are found in fish, walnuts, ground flaxseeds and flaxseed oil. Ground flaxseeds should be kept in the freezer, and can be found combined with ground almonds and sunflower seeds, as "LSA".

• Stress less.
Stress is a major contributor to the development of many diseases, but particularly heart disease. Having chronically elevated stress hormones running through your bloodstream promotes inflammation and weakens your immune system. It is important to make time to do things you enjoy, and surround yourself with a network of people you love.

• Exercise is a must.
It will help to keep your weight down, greatly reduce the risk of Syndrome X and diabetes and it is an excellent stress buster. Exercise helps to keep your LDL "bad" cholesterol and triglycerides down, and is one of the few ways to raise your levels of HDL "good" cholesterol.

• Get lots of antioxidants into your diet.
It is not cholesterol, but rather oxidized cholesterol that does the harm to your arteries. You need plenty of antioxidants to prevent the cholesterol in your body from oxidizing. You can do this by ensuring you get the recommended five servings of vegetables and two servings of fruit each day. Making your own raw vegetable juices regularly is a sure way of getting enough fruit and veggies. Antioxidants are also found in raw nuts and seeds, legumes, green tea, red wine and dark chocolate.

*58/53/5*
CHOLESTEROL

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