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Generic Anaprox (Naproxen 275/500mg)
- Denomination
Naprosyn
- Active Substance
Naproxen
- Indications for Use.
· rheumatoid arthritis;
· osteoarthritis;
· ankylosing spondylitis;
· acute fit of gout;
· pains in the spine;
· neuralgias;
· myalgias;
· traumatic inflammation of soft tissues and locomotor apparatus;
· primary dysmenorrhea.
- Action
Naproxen takes evidenced anti-inflammatory, nonnarcotic, antipyretic action.
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Posology and Administration
Naproxen should be taken orally. Tablets should be taken in whole, rinsing them with liquid; they are possible to be taken during meal. In acute stage of the disease they may be taken 0.5-0.75 g each 2 times a day. The maximal daily dose is 1.75 g. For maintenance therapy an average daily dose should be 500 mg in 2 intakes (in the morning and before bedtimeу). When there is acute fit of gout the first dose should be 825 mg; then 275 mg every 8 hours. In event of menstrual colic the first dose should be 500 mg, and then there should be 275 mg each every 6-8 hours during 3-4 days. In event of migraine a dose should be 500 mg. Rectal suppositories usually are administered before bedtime (one suppository of 0.5 g each). If it is a need to use Naproxen in high doses it is possible to combine administrations in suppositories and tablet. In children of the age from 1 year to 5 years the drug should be administered in a daily dose of 2.5-5 mg/kg in 1-3 intakes; a course of the treatment should not exceed 14 days. In event of juvenile arthritis in children over 5 years of age a daily dose should be 10 mg/kg. Suspension is a preferable drug formulation for children.
- Counterindications
ulcer disease of stomach and duodenal in an aggravation phase;
bronchial spasm fits due to NSAID administration (in anamnesis);
hemorrhagic diathesis;
pregnancy;
childhood (under 16 year of age);
hypersensitivity to Naproxen
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Should Be Taken with Precautions, if…
Care should be taken in administering of Naproxen to the patients with compromised functions of liver and/or kidneys, gastrointestinal diseases, arterial hypertension, heart failure, immediately after a serious surgery interventions.
Caution is needed in administration of Naproxen to elderly people, especially in compromised kidneys function.
There should be taken in consideration that Naproxen increases bleeding time.
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Interface with Other Medications
Attention!
Before the application of Naproxen a doctor’s advice is needed. Naproxen in simultaneous use with other drugs may provoke either effect reduction or effect enhancement.
- Overdosing
Symptoms: drowsiness, heartburn, dyspepsia, nausea, vomit.
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Side Effects
On the part of gastrointestinal tract: nausea, vomit, constipation, discomfort sensation in the pit of the stomach, seldom – stomach bleeding.
On the part of central nervous system and sense organs: headache, drowsiness, seldom – hearing disorders, visual distortion.
Allergic and immunopathological reactions: skin rash, hives, Quincke’s disease; seldom – hemolytic anemia, thrombocytopenia, agranulocytosis.
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Pregnancy and Lactation
Should be taken with caution in pregnancy (especially in the I-st and III-d trimesters) and lactation period.
Naproxen penetrates through placental barrier and excretes with breast milk in small quantities.
- Driving
In event of drowsiness and “haziness” of vision, weakness, vehicles driving and other alertness-requiring actions should be avoided.
PHYSICAL ACTIVITIES FOR PATIENTS WITH OSTEOARTHRITIS
Osteoarthritis is predominantly characterized by erosion of the articular cartilage due to either primary or secondary trauma, mostly on weight-bearing joints. A consensus report states that there is no evidence for a preventive effect of physical activity on osteoarthritis in weight-bearing joints. Also, there is no evidence that inactivity of a joint alone directly produces osteoarthritis. However, physical inactivity is often associated with obesity, and obesity increases the risk of osteoarthritis. Moreover, individuals with osteoarthritis who are inactive for prolonged periods of time are likely to have poor aerobic capacity and therefore are at increased risk for cardiovascular disease and other inactivity-related conditions.
Epidemiologic studies have demonstrated that participation in certain competitive sports demanding high-intensity, acute, direct joint impact as a result of contact with other participants, playing surfaces, or equipment increases the risk for osteoarthritis. Repetitive joint impact and torsional loading (twisting) also appear to be associated with joint degeneration, as seen in the elbows of baseball pitchers and the knees of soccer players. Note, however, that those who engage in moderate-intensity physical activity are at zero to low risk of osteoarthritis.
The fact that low-intensity running has perhaps no association with osteoarthritis, whereas soccer does, illustrates the concept that appropriate physical activities should be selected for reduced risk of chronic health conditions. Not all types of exercise are associated with development of osteoarthritis.
It is well recognized that patients with osteoarthritis of the knee develop quadriceps muscle weakness, which is often attributed to physical inactivity and is presumed to develop because the patient minimizes use of the painful limb. Evidence is also growing that deconditioned muscle, inadequate motion, and periarticular stiffness may contribute to signs and symptoms of osteoarthritis.
Exercise is integral in reducing impairment, improving function, and preventing disability in osteoarthritic patients. Some of the physical activity benefits accruing in patients with osteoarthritis are: flexibility, muscular conditioning, and cardiovascular and general health. Both therapeutic and recreational physical activity (especially that of moderate intensity and duration) is an effective therapy for the successful management of osteoarthritis.
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HEALTHY BONES
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A. Refund Policy
Q. Can you tell me if I should be taking Generic Anaprox ( Naproxen 275/500mg ) ? Or, will it work for me?
A. We cannot advise you in any capacity in this matter. You should not take any medication without consulting a physician first.
Q. What is your returns policy?
A. By law, we regret that we are unable to accept returned pharmaceuticals. If your purchase is defective in any way, we will be pleased to replace it at no cost to you.
Q. What about importing of Generic Anaprox ( Naproxen 275/500mg ) to my country ?
A. Importation of prescription medication is legal in most countries (including the US, UK, France, Spain, Hong Kong, Japan and S. Korea) provided the medication is for personal use and is not a controlled substance. If you are in doubt about the situation in your country, check with your local Post Office.
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