Generic Albuterol Cr

1. Denomination

Proventil, Ventolin

2. Active Substance

Albuterol, Salbutamol

3. Indications for Use.

Prevention and stopping of bronchospasm in cases of bronchial asthma, symptomatic treatment of broncho-obstructive syndrome (chronic bronchitis, chronic obstructive lung disease etc.), nocturnal asthma (prolonged tableted forms); prevention of premature birth.

4. Action

The drug increases activity of stimulators of central nervous system. It gives effect caused be relaxation of smooth muscles of bronchi. Salbutamol acts long. It retards contractive activity of the womb, prevents premature birth.

5. Posology and Administration

Orally: adults and children over 12 years of age are administered 2-4 mg 3-4 times daily, if needed - a dose may be increased up to 8 mg 4 times a day. The maximal daily dose is 32 mg. Children 6-12 years of age are administered 2 mg 3-4 times daily, the maximal dose is 24 mg/daily; children 2-6 years of age 1-2 mg (0.1 mg/kg) 3-4 times a day. Sustained action tablets: in adults and children over 12 years of age are taken 4-8 mg every 12 hour; the maximal dose is 32 mg/daily (16 mg every 12 hours); in children 6-12 years of age 4 mg every 12 hours, the maximal dose is 24 mg/daily (12 mg every 12 hours). Swallow tablets whole.

6. Counterindications

Hypersensitivity, ischemic heart disease, high arterial tension, rhythm disturbance, heart disorder, diabetes, hyperthyrosis, tumors, compromised kidney function, I-st trimester of pregnancy, pregnancy (when used in a quality of bronchial spasmolytic), lactation period, childhood (less than 6 years of age – for tablets administration, less than 2 years of age for orally eligible solution and syrup administration).

7. Should Be Taken with Precautions, if…

Frequent use of Salbutamol may result in the enhancement of bronchospasm and unexpected death; therefore between intakes of regular doses of the drug it is necessary to make several hours’ intervals (6 hours). Only in exception cases the intervals may be reduced. Failing any minimal of the use of inhalation or in cases of evidenced tremor, tachycardia, heart rhythm disorder it is counterindicated a further use of inhalator; and it is necessary to see your doctor. Risk of aggravations grows both if the treatment is significantly long and if the drug administration is abruptly cancelled.

8. Interface with Other Medications

Interaction with other medications may give unpredictable side effects. Therefore it is recommended to notify your doctor which medications you are taking or have taken lately. On the matter of combination of drugs it is necessary to consult your doctor.

9. Overdosing

Symptoms: tachycardia, ventricular flutter, dilatation of peripheral vessels, low arterial tension, increase of cardiac output, oxygen hunger, jerks, headache, agitation, hallucinations etc, psychotic disorders.

10. Side Effects

Dizziness, headache, tachycardia (in the period of pregnancy in mother and in fetus), arrhythmia, myocardial ischemia, heart failure, pulmonary edema (lethal outcome is possible), blush, disordered uncontrolled waving of limbs, nausea, vomiting, dry mouth, loss of appetite, stanguria, perspiration, allergic reactions in the form of blubs, dropsical face, rough breathing, progression of physical and psychic drug dependence.

11. Pregnancy and Lactation

Caution should be taken in the use of Salbutamol in pregnancy and in lactation.
If there is a need of the drug administration in the period of lactation breast-feeding should be stopped (it is unknown whether Salbutamol excretes into breast milk).

12. Driving

For your safety before you start to drive a car find out your individual reaction to Salbutamol.

 ATHEROSCLEROSIS (ATHEROMA)
Unhappily, few hearts in people living in developed countries have coronary blood vessels that fulfill that ideal, and why this should be is encapsulated in one word—atherosclerosis. The word atherosclerosis comes from the Greek word for porridge, atheros. It was first used to describe atheromatous patches seen in the inside surfaces of the large arteries, particularly the aorta (the main artery from the left side of the heart to the body), that look grainy, soft, and crumbly—very much like porridge.
Atherosclerosis was then extended to describe the process seen inside the coronary arteries in people who have angina or who have had heart attacks. In its later stages, atheroma causes the coronary arteries to narrow, so that less blood can flow through them. It also makes them less elastic, so that they cannot expand to cope with an increased demand for blood.
If you have atheroma of the coronary arteries, the supply side of the supply-demand equation may be compromised, and the conditions for angina are established. Whether you have angina or not depends on the extent of the blockage and on whether there is one particular site in a coronary artery that is especially affected, so that the blood supply beyond it is greatly diminished.
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